HR1 BRCA 1/2 FFPE + BLOOD SAMPLE

4bases HR1 BRCA 1/2 is a clinically validated CE-IVD kit for the identification of both somatic and germline mutations in BRCA 1 and BRCA 2 genes using DNA from routinely available FFPE tissue or blood samples.

HR1BRCA

KEY FEATURES

 

  • Code: 1-2000-1-16; IL1-2000-1-16
  • Number of test: 16
  • Gene targeted: BRCA1, BRCA2, TP53
  • Application: somatic, germline

 

  • Number of pool: 3
  • Panel size: 26 kb
  • Input DNA: 20ng/reaction
  • Coverage: full exons plus 20bp padding regions

 

 

SAMPLE/RUN

  Germline Somatic
PGM 314 chip  2  -
PGM 316 chip  10  2
PGM 318 chip  20  3
S5 520 chip  20  3
S5 540 chip  85  14
MiSeq Reagent Nano Kit v2 (300 cycles)  5  1
MiSeq Reagent Micro Kit v2 (300 cycles)  20  3
MiSeq Reagent Kit v2 (300 cycles)  75  12
MiniSeq High Output Kit (300 cycles)  120  18
MiniSeq Mid Output Kit (300 cycles)  40  6

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Scientific publication

Workflow

Required materials and instruments

 

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HEVA Screen

4bases HEVA Screen is a clinically validated kit for the identification of hereditary variants associated with breast, ovarian and polyposis colorectal cancer risk.

HEVA Screen esagoni con CEIVD per sito 06

 

KEY FEATURES

 

  • Code: 1-2001-1-16; IL1-2001-1-16
  • Number of test: 16
  •  Gene targeted: ATM, APC, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, EPCAM, MLH1, MSH2, MSH6, MUTYH, NBN, PALB2, PMS2, PTEN, RAD50, RAD51C, RAD51D, STK11, TP53
  • Application: germline

 

  • Number of pool: 3
  • Panel size: 145 kb
  • Input DNA: 10ng/reaction
  • Coverage: full exons plus 20bp padding regions

SAMPLE/RUN

  Germline  
PGM 314 chip  1  
PGM 316 chip  4  
PGM 318 chip  8  
     
S5 520 chip  8  
S5 540 chip  30   
     
MiSeq Reagent Nano Kit v2 (500 cycles)  2  
MiSeq Reagent Kit v2 (500 cycles)  24  
MiSeq Reagent Kit v3 (600 cycles)  40   

 

MORE ABOUT

Scientific publication

Workflow

Required materials and instruments

 

Download

 

 

 
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